Postoperative high blood sugar levels may increase the risk for infection at the surgical site in patients having general surgery. The study examined 1,561 patients, including 559 who had vascular surgery, 226 who had colorectal surgery and 776 who had a type of general surgery other than colorectal. Age, emergency status, physical status as classified by the American Society of Anesthesiologists, time in surgery, diabetes and high postoperative blood glucose were all factors that appeared to be associated with surgical site infections, but factors other than postoperative blood glucose level were not significant predictors of infection. "In conclusion, we found postoperative hyperglycemia to be the most important risk factor for surgical site infection in general and colorectal cancer surgery patients, and serum glucose levels higher than 110 milligrams per deciliter were associated with increasingly higher rates of post-surgical infection," the researchers wrote.

Duke University Medical Center researchers said they found that surgically implanted antibiotic-infused sponges do not reduce the rate of sternal wound infections in patients who have had heart surgery. Gentamicin-collagen sponges, approved in 54 countries, not including the U.S., are used in more than 1 million people. The study of 1,502 heart surgery patients found there was no significant difference in the overall rates of sternal wound infections between people who received sponges and those who did not.

A study examined 7,000 patients undergoing elective, inpatient orthopedic procedures at New England Baptist Hospital in Boston who were screened for methicillin-sensitive Staphlylococcus aureus and MRSA. Patients who tested positive were instructed via pre-op phone calls to apply mupiricin ointment to the interior of each naris, and patients who still carried MRSA after the application of the ointment were treated with standard MRSA isolation precautions in addition to pre-op antibiotics. The study showed that the surgical site infection rate dropped 59 percent when the prescreening program was in place. The researchers suggested the drop in SSIs was likely due to the ability of clinicians to switch preoperative antibiotic prophylaxis to vancomycin, as well as the treatments with the ointment. The researchers concluded that prescreening programs are "feasible and can lead to significant reductions in postoperative rates of surgical site infection."

Die National Conference of State Legislatures (NCSL) hat einen neuen Bericht veröffentlicht, in dem wichtige Einsichten aus Daten zur Infektionsmeldung von neun Bundesstaaten ausgewertet werden, die medizinische Einrichtungen als erstes einer Meldepflicht für nosokomiale Infektionen unterworfen haben. Die NCSL befasste sich mit Gesetzen auf Bundesstaatenebene, die zwischen 2005 und 2009 erlassen wurden, und befragte Abgeordnete, medizinische Fachkräfte und andere beteiligte Gruppen in Alabama, Colorado, Delaware, Illinois, Massachusetts, New Hampshire, Oregon, Pennsylvania und Washington. Seit 2005 ist die Anzahl der Bundesstaaten, in denen Gesundheitseinrichtungen zur Meldung von NIs verpflichtet sind, von sechs auf 27 gestiegen.

Leaving an antibiotic-soaked collagen sponge in the wound after colorectal surgery "paradoxically" seemed to cause an increase in surgical site infections. The findings of Elliott Bennett-Guerrero of Duke Clinical Research Institute in Durham, N.C., and colleagues opposed findings of an earlier study that identified a 70 percent decrease in such infections with the use of a gentamicin-collagen sponge. The study involved 602 patients undergoing open or laparoscopically assisted colorectal surgery at 39 U.S. sites.

Epidrual or spinal anesthesia may help curb the risk of surgical site infection when compared with the use of general anesthesia in patients undergoing total joint replacement surgery. In an editorial on the study, Daniel I. Sessler of the Cleveland Clinic Anesthesiology Institute’s Department of Outcomes Research, said the findings provide compelling epidemiologic evidence that neuraxial anesthesia reduces the risk of SSIs. The study examined 3,081 patients in Taiwan who underwent total knee and total hip replacement procedures, and it showed that SSI rates within 30 days of the procedure was 2.2 times greater in patients who had general anesthesia.

Patients who have had major chest or head operations are at an increased risk of developing post-surgical staphylococcus aureus infections. The findings are based on a review of 81,267 patients who underwent 96,455 orthopedic, cardiothoracic, plastic surgery or neurosurgery procedures at nine locations between 2003 and 2006. There were 454 staph infections among the patients, with the highest rates of bloodstream infections occurring in patients who had chest surgery, while the highest rates of surgical site infections occurred in patients who had brain operations. Deverick Anderson, lead author from Duke University Medical Center, said additional preventions for cardiovascular or neurosurgical procedures may be needed.

Patients might have a higher risk of developing invasive Staphylococcus aureus infections after cardiothoracic and neurosurgical procedures when compared with orthopedic or plastic surgical procedures, according to a study published in Infection Control and Hospital Epidemiology. Lead author Deverick Anderson and his team of researchers from Duke University Medical Center studied the postsurgical outcomes of 96,455 procedures from 11 hospitals. Included in the analysis were individuals who had undergone orthopedic, neurosurgical, cardiothoracic and plastic surgical procedures between 2003 and 2006. The breakdown of MRSA infections ranged from 62 percent following cardiothoracic surgery to 35 percent following plastic surgery, the investigators found.